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Biomarkers in Cancer Screening and Early Detection by Sudhir Srivastava (English
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Specificaties
- Objectstaat
- ISBN-13
- 9781118468807
- Book Title
- Biomarkers in Cancer Screening and Early Detection
- ISBN
- 9781118468807
- Subject Area
- Science, Medical
- Publication Name
- Biomarkers in Cancer Screening and Early Detection
- Publisher
- Wiley & Sons, Incorporated, John
- Item Length
- 9.8 in
- Subject
- Life Sciences / Biochemistry, Oncology
- Publication Year
- 2017
- Series
- Translational Oncology Ser.
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Height
- 0.8 in
- Item Weight
- 31.3 Oz
- Item Width
- 7.2 in
- Number of Pages
- 320 Pages
Over dit product
Product Information
Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and clinical use. The primary purpose of this book is to summarize and present best practices in this field to date, and offer actionable information and hopefully also inspiration to move discovery and clinical application forward. This latest volume of the Translational Oncology series, Biomarkers in Cancer Screening and Early Detection is organized into three sections: Section I lays the foundation for biomarker discovery, development and validation. Section II presents organ-specific topics relevant to the clinical needs in early detection, the natural history of the disease and associated evidence in support of biomarker research, an overview of the current state-of-the art in biomarker research, current progress toward bringing these biomarkers into clinical use and the future of biomarker-based screening and early detection for the respective organ type. Finally, Section III offers chapters that address the current screening strategies for selected organ types, discuss deficiencies with the present practice and identify clinical needs that may benefit from biomarker-based approaches. This latest volume of the Translational Oncology series, Biomarkers in Cancer Screening and Early Detection: Provides immediately actionable information and hopefully also inspiration to move discovery and clinical application forward Considers the cutting edge "bench to bedside and back" breakthroughs which have transformed the diagnosis, prognosis and treatment of cancer Discusses screening guidelines, research strategies, and issues surrounding cancer overdiagnosis Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers The development of cancer is preceded by numerous mutations and changes which transform normal cells into benign tumors, and progressively into malignant and metastatic forms. This enormous complexity makes cancer detection, diagnosis, and treatment challenging and therefore the ability to identify tumors that are destined to progress at an early stage will allow effective treatment interventions and reduce deaths. This new book comprehensively summarises the current state of play and is an ideal resource for clinical and research oncologists interested in the progress of screening and detection of cancer.
Product Identifiers
Publisher
Wiley & Sons, Incorporated, John
ISBN-10
1118468805
ISBN-13
9781118468807
eBay Product ID (ePID)
224011190
Product Key Features
Number of Pages
320 Pages
Language
English
Publication Name
Biomarkers in Cancer Screening and Early Detection
Publication Year
2017
Subject
Life Sciences / Biochemistry, Oncology
Type
Textbook
Subject Area
Science, Medical
Series
Translational Oncology Ser.
Format
Hardcover
Dimensions
Item Height
0.8 in
Item Weight
31.3 Oz
Item Length
9.8 in
Item Width
7.2 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2017-022050
Dewey Edition
23
Series Volume Number
3
Dewey Decimal
616.99/4075
Lc Classification Number
Rc270.3.T84
Table of Content
List of Contributors, ix Preface, xiii Part I Foundations of Biomarker Research 1 Nuts and Bolts of Biomarker Research, 3 Sharmistha Ghosh and Sudhir Srivastava 2 Cancer Genome Methylation: Biology, Biomarker and Therapeutic Opportunities, 16 Shashwat Sharad, Taduru Sreenath, Shiv Srivastava, and Albert Dobi 3 MicroRNA Biomarkers for Early Detection of Cancer, 27 WendyWang, Matthew R Young, and Sudhir Srivastava 4 Inflammation and Cancer, 37 Pamela L Beatty, Sandra Cascio, and Olivera J Finn 5 Exosomes: A Valuable Biomedical Tool in Biomarker Discovery and Development, 50 Jocelyn Lee, Sharmistha Ghosh, and Sudhir Srivastava 6 Epithelial-to-Mesenchymal Transition (EMT): Clinical Implications, 64 Elisa CWoodhouse and Suresh Mohla Part II State-of-the-Science in Organ-Specific Biomarker Research 7 Breast Cancer, 77 Benjamin A Katchman, Christos Patriotis, and Karen S Anderson 8 Ovarian Cancer, 93 Christos Patriotis, Archana Simmons, Karen H Lu, Robert C Bast, Jr, and Steven J Skates 9 Esophageal Cancer Biomarkers, 104 Yanxin Luo, Kishore Guda, SanfordD Markowitz, Amitabh Chak, Andrew M Kaz, andWilliam M Grady 10 Predictive Biomarkers for Therapy in Adenocarcinoma of the Upper Digestive Tract, 118 Heath D Skinner, Qiongrong Chen, Elena Elimova, RoopmaWadhwa, Shumei Song, and Jaffer A Ajani 11 Pancreatic Cancer, 130 Sam CWang and Peter J Allen 12 Colon Cancer, 141 Paul DWagner 13 Prognostic and Predictive Biomarkers for Colorectal Cancer, 151 Upender Manne, Balananda-Dhurjati Kumar Putcha, Temesgen Samuel, and Sudhir Srivastava 14 Early Detection of Lung Cancer, 163 Mohamed Hassanein, Melinda C Aldrich, Stephen A Deppen, Karl E Krueger, Eric L Grogan, and Pierre P Massion 15 Commonalities in Lung Cancer and COPD, 185 MalgorzataWojtowicz and Eva Szabo 16 Prostate Cancer, 197 Jacob Kagan, Ian M Thompson, and DanielWChan Part III Biomarkers, Screening and Precision Health: Implications for Public Health 17 Improving the Clinical Validity of Biomarker Research in Cancer Detection, 209 David F Ransohoff 18 Cancer Overdiagnosis, Ramifications and Research Strategies, 220 Barbara K Dunn and Barnett S Kramer 19 Predictive Markers and Driver Genes From Treatment Trials: Potential Utility For Early Diagnosis, 231 Brian S Sorg, Sarfraz Memon, Kelly Y Kim, Aniruddha Ganguly, Tracy Lively, James Tricoli, Magdalena Thurin, Lokesh Agrawal, Tawnya C McKee, Barbara A Conley, and J Milburn Jessup 20 Statistical Consideration in Predictive and Prognostic Markers, 245 Fei Ye and Yu Shyr 21 Clinical Validation of Molecular Biomarkers in Translational Medicine, 256 Harry B Burke and William E Grizzle 22 Cancer Biomarker Assays: Performance Standards, 267 Anna K Fuzery and Daniel W Chan 23 Bioethics and Cancer Biomarker Research, 277 Nathan Nobis, William Grizzle, and Stephen Sodeke 24 Colon Cancer Screening, 283 Molly Perencevich, Jennifer Inra, and Sapna Syngal
Copyright Date
2017
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