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The Squid Giant Synapse: A Model for Chemical Transmission by Rodolfo R Llinas
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eBay-objectnummer:285114492481
Specificaties
- Objectstaat
- Book Title
- The Squid Giant Synapse: A Model for Chemical Transmission
- Publication Date
- 1999-10-28
- Pages
- 240
- ISBN
- 9780195116526
- Publication Year
- 1999
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- Squid Giant Synapse : a Model for Chemical Transmission
- Item Height
- 0.8in
- Item Length
- 9.3in
- Publisher
- Oxford University Press, Incorporated
- Item Width
- 6.1in
- Item Weight
- 17.6 Oz
- Number of Pages
- 240 Pages
Over dit product
Product Information
The squid giant synapse is the single most important model for investigating the transmitter release mechanism in chemical junctions. This unique book, by a leading expert in the field, gives a concise overview of all that has been learned about synaptic transmission in this superb model system. It covers in detail the biophysics of the voltage-dependent calcium currents, calcium concentration microdomains, and much of the molecular basis for the triggering of the secretory event. Ideal for graduate and undergraduate courses, the book includes PC and Macintosh versions of two programs for simulating and manipulating any aspect of synaptic transmission. One program is a modeling tool designed for working neuroscientists, and the other teaches the basic principles of synaptic transmission by allowing students to alter the parameters, essentially without limits, and see the effects on the action potential over time. Anyone studying this central topic of neuroscience will find this book an invaluable resource.
Product Identifiers
Publisher
Oxford University Press, Incorporated
ISBN-10
0195116526
ISBN-13
9780195116526
eBay Product ID (ePID)
727989
Product Key Features
Publication Name
Squid Giant Synapse : a Model for Chemical Transmission
Format
Hardcover
Language
English
Publication Year
1999
Type
Textbook
Number of Pages
240 Pages
Dimensions
Item Length
9.3in
Item Height
0.8in
Item Width
6.1in
Item Weight
17.6 Oz
Additional Product Features
Lc Classification Number
Qp364.L56 1999
Reviews
"When it comes to contributing to our knowledge of neuronal function, no creature can surpass the squid. Its axon has enabled us to discover the ionic basis of electrical signalling, and its synapse has revealed the chemical signalling between neurons. Rodolfo Llinas' book summarizes what thisinvertebrate has told us about chemical synaptic transmission. . . . It should . . . attract a wide audience, particularly those interested in listening to nature directly rather than passively accepting current paradigms. Finally, the book comes with a CD-Rom containing an excellent program of asynaptic model. . . . This program will surely attract young students, as well as researchers, who are interested in computer simulations of neuronal function. This model also reminds us of the dynamic aspects of synaptic function and that individual neurons are not merely passive elements inneuronal networks, but actively influence brain function through synaptic modulation."--Nature, "Given that the brain consists of some 100 billion nerve cells, understanding how synapses allow these cells to communicate with each other has been a core question in neuroscience. The past 50 years have seen remarkable advances in this area, largely due to a small number of experimental systems--such as neuromuscular synapses and the squid giant synapse--whose great advantages for physiological analyses have illuminated the beauty of synaptic function. Thus a book, such as The Squid Giant Synapse, that concisely highlights the contributions of one such model system is a very good idea. An even better idea is to have the book written by Rodolfo Llins, a distinguished synaptic physiologist . . . Llins has done a good job of capturing the excitement that has kept the field of synaptic physiology energized. By its example, he Squid Giant Synapse offers a strong argument for the continued value of physiological analyses of brain function, even in these genomic times."--Science "When it comes to contributing to our knowledge of neuronal function, no creature can surpass the squid. Its axon has enabled us to discover the ionic basis of electrical signalling, and its synapse has revealed the chemical signalling between neurons. Rodolfo Llinas' book summarizes what this invertebrate has told us about chemical synaptic transmission. . . . It should . . . attract a wide audience, particularly those interested in listening to nature directly rather than passively accepting current paradigms. Finally, the book comes with a CD-Rom containing an excellent program of a synaptic model. . . . This program will surely attract young students, as well as researchers, who are interested in computer simulations of neuronal function. This model also reminds us of the dynamic aspects of synaptic function and that individual neurons are not merely passive elements in neuronal networks, but actively influence brain function through synaptic modulation."--Nature, "Given that the brain consists of some 100 billion nerve cells, understanding how synapses allow these cells to communicate with each other has been a core question in neuroscience. The past 50 years have seen remarkable advances in this area, largely due to a small number of experimentalsystems--such as neuromuscular synapses and the squid giant synapse--whose great advantages for physiological analyses have illuminated the beauty of synaptic function. Thus a book, such as The Squid Giant Synapse, that concisely highlights the contributions of one such model system is a very goodidea. An even better idea is to have the book written by Rodolfo Llinas, a distinguished synaptic physiologist . . . Llinas has done a good job of capturing the excitement that has kept the field of synaptic physiology energized. By its example, he Squid Giant Synapse offers a strong argument forthe continued value of physiological analyses of brain function, even in these genomic times."--Science, "When it comes to contributing to our knowledge of neuronal function, nocreature can surpass the squid. Its axon has enabled us to discover the ionicbasis of electrical signalling, and its synapse has revealed the chemicalsignalling between neurons. Rodolfo Llinas' book summarizes what thisinvertebrate has told us about chemical synaptic transmission. . . . It should .. . attract a wide audience, particularly those interested in listening tonature directly rather than passively accepting current paradigms. Finally, thebook comes with a CD-Rom containing an excellent program of a synaptic model. .. . This program will surely attract young students, as well as researchers, whoare interested in computer simulations of neuronal function. This model alsoreminds us of the dynamic aspects of synaptic function and that individualneurons are not merely passive elements in neuronal networks, but activelyinfluence brain function through synaptic modulation."--Nature, "Given that the brain consists of some 100 billion nerve cells,understanding how synapses allow these cells to communicate with each other hasbeen a core question in neuroscience. The past 50 years have seen remarkableadvances in this area, largely due to a small number of experimentalsystems--such as neuromuscular synapses and the squid giant synapse--whose greatadvantages for physiological analyses have illuminated the beauty of synapticfunction. Thus a book, such as The Squid Giant Synapse, that conciselyhighlights the contributions of one such model system is a very good idea. Aneven better idea is to have the book written by Rodolfo Llinas, a distinguishedsynaptic physiologist . . . Llinas has done a good job of capturing theexcitement that has kept the field of synaptic physiology energized. By itsexample, he Squid Giant Synapse offers a strong argument for the continued valueof physiological analyses of brain function, even in these genomictimes."--Science, "Given that the brain consists of some 100 billion nerve cells, understanding how synapses allow these cells to communicate with each other has been a core question in neuroscience. The past 50 years have seen remarkable advances in this area, largely due to a small number of experimental systems--such as neuromuscular synapses and the squid giant synapse--whose great advantages for physiological analyses have illuminated the beauty of synaptic function. Thus a book, such asThe Squid Giant Synapse, that concisely highlights the contributions of one such model system is a very good idea. An even better idea is to have the book written by Rodolfo Llin s, a distinguished synaptic physiologist . . . Llin s has done a good job of capturing the excitement that has kept the field of synaptic physiology energized. By its example, he Squid Giant Synapse offers a strong argument for the continued value of physiological analyses of brain function, even in these genomic times."--Science "When it comes to contributing to our knowledge of neuronal function, no creature can surpass the squid. Its axon has enabled us to discover the ionic basis of electrical signalling, and its synapse has revealed the chemical signalling between neurons. Rodolfo Llinas' book summarizes what this invertebrate has told us about chemical synaptic transmission. . . . It should . . . attract a wide audience, particularly those interested in listening to nature directly rather than passively accepting current paradigms. Finally, the book comes with a CD-Rom containing an excellent program of a synaptic model. . . . This program will surely attract young students, as well as researchers, who are interested in computer simulations of neuronal function. This model also reminds us of the dynamic aspects of synaptic function and that individual neurons are not merely passive elements in neuronal networks, but actively influence brain function through synaptic modulation."--Nature, "Given that the brain consists of some 100 billion nerve cells, understanding how synapses allow these cells to communicate with each other has been a core question in neuroscience. The past 50 years have seen remarkable advances in this area, largely due to a small number of experimental systems--such as neuromuscular synapses and the squid giant synapse--whose great advantages for physiological analyses have illuminated the beauty of synaptic function. Thus a book, such as The Squid Giant Synapse, that concisely highlights the contributions of one such model system is a very good idea. An even better idea is to have the book written by Rodolfo Llinás, a distinguished synaptic physiologist . . . Llinás has done a good job of capturing the excitement that has kept the field of synaptic physiology energized. By its example, he Squid Giant Synapse offers a strong argument for the continued value of physiological analyses of brain function, even in these genomic times."--Science "When it comes to contributing to our knowledge of neuronal function, no creature can surpass the squid. Its axon has enabled us to discover the ionic basis of electrical signalling, and its synapse has revealed the chemical signalling between neurons. Rodolfo Llinas' book summarizes what this invertebrate has told us about chemical synaptic transmission. . . . It should . . . attract a wide audience, particularly those interested in listening to nature directly rather than passively accepting current paradigms. Finally, the book comes with a CD-Rom containing an excellent program of a synaptic model. . . . This program will surely attract young students, as well as researchers, who are interested in computer simulations of neuronal function. This model also reminds us of the dynamic aspects of synaptic function and that individual neurons are not merely passive elements in neuronal networks, but actively influence brain function through synaptic modulation."--Nature, "The Squid Giant Synapse...concisely highlights the contributions of onesuch model system is a very good idea. An even better idea is to have the bookwritten by Rodolfo Llinas, a distinguished synaptic physiologist who now hasbeen working on this preparation for five decades....the value of this book liesin its personal narration of one scientist's journey through the synapse. Llinashas done a good job of capturing the excitement that has kept the field ofsynaptic physiology energized. By its example, he Squid Giant Synapse offers astrong arguement for the continued value of physiological analyses of brainfunction, even in these genomic times."--Science, "Given that the brain consists of some 100 billion nerve cells, understanding how synapses allow these cells to communicate with each other has been a core question in neuroscience. The past 50 years have seen remarkable advances in this area, largely due to a small number of experimental systems--such as neuromuscular synapses and the squid giant synapse--whose great advantages for physiological analyses have illuminated the beauty of synaptic function. Thus a book, such as The Squid Giant Synapse, that concisely highlights the contributions of one such model system is a very good idea. An even better idea is to have the book written by Rodolfo Llinás, a distinguished synaptic physiologist . . . Llinás has done a good job of capturing the excitement that has kept the field of synaptic physiology energized. By its example, he Squid Giant Synapse offers a strong argument for the continued value of physiological analyses of brain function, even in these genomic times."--Science"When it comes to contributing to our knowledge of neuronal function, no creature can surpass the squid. Its axon has enabled us to discover the ionic basis of electrical signalling, and its synapse has revealed the chemical signalling between neurons. Rodolfo Llinas' book summarizes what this invertebrate has told us about chemical synaptic transmission. . . . It should . . . attract a wide audience, particularly those interested in listening to nature directly rather than passively accepting current paradigms. Finally, the book comes with a CD-Rom containing an excellent program of a synaptic model. . . . This program will surely attract young students, as well as researchers, who are interested in computer simulations of neuronal function. This model also reminds us of the dynamic aspects of synaptic function and that individual neurons are not merely passive elements in neuronal networks, but actively influence brain function through synaptic modulation."--Nature, "Given that the brain consists of some 100 billion nerve cells, understanding how synapses allow these cells to communicate with each other has been a core question in neuroscience. The past 50 years have seen remarkable advances in this area, largely due to a small number of experimental systems--such as neuromuscular synapses and the squid giant synapse--whose great advantages for physiological analyses have illuminated the beauty of synaptic function. Thus a book, such as The Squid Giant Synapse , that concisely highlights the contributions of one such model system is a very good idea. An even better idea is to have the book written by Rodolfo Llinás, a distinguished synaptic physiologist . . . Llinás has done a good job of capturing the excitement that has kept the field of synaptic physiology energized. By its example, he Squid Giant Synapse offers a strong argument for the continued value of physiological analyses of brain function, even in these genomic times."-- Science "When it comes to contributing to our knowledge of neuronal function, no creature can surpass the squid. Its axon has enabled us to discover the ionic basis of electrical signalling, and its synapse has revealed the chemical signalling between neurons. Rodolfo Llinas' book summarizes what this invertebrate has told us about chemical synaptic transmission. . . . It should . . . attract a wide audience, particularly those interested in listening to nature directly rather than passively accepting current paradigms. Finally, the book comes with a CD-Rom containing an excellent program of a synaptic model. . . . This program will surely attract young students, as well as researchers, who are interested in computer simulations of neuronal function. This model also reminds us of the dynamic aspects of synaptic function and that individual neurons are not merely passive elements in neuronal networks, but actively influence brain function through synaptic modulation."-- Nature
Table of Content
1. Introduction2. Electrophysiological Studies3. Presynaptic Calcium Current and Transmitter Release4. Molecular Mechanism5. Toxins and Transmitter Release6. Peptides and Kinases7. Concluding Remarks
Copyright Date
1999
Topic
Neurology, Neuroscience, Animals / Marine Life, General
Lccn
98-038419
Dewey Decimal
573.8/61458
Intended Audience
College Audience
Dewey Edition
21
Illustrated
Yes
Genre
Nature, Medical
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